Research Opportunities in Myeloma Pathobiology and Immuno-oncology Therapeutics
Job posting number: #7077999
Posted: May 7, 2021
Job DescriptionResearchers interested in postdoctoral fellowships are invited to apply for positions as part of the group led by Dr. Robert Orlowski, Florence Maude Thomas Cancer Research Professor and Director of the Myeloma Section in the Department of Lymphoma/Myeloma at The University of Texas MD Anderson Cancer Center. Our focus is on developing an expanded understanding of the molecular pathobiology of multiple myeloma and related disorders, validating novel targets and therapeutics that can be translated to the clinic, and understanding mechanisms of resistance that could serve as biomarkers and/or targets for chemosensitization. Current projects of interest focus on the activity of a novel, home-grown set of patented monoclonal antibodies that are showing immunomodulatory and direct cytotoxic activity against a variety of tumor models as naked antibodies and antibody-drug conjugates. A second area of interest is in the use of pre-clinical modeling and clinical sample interrogation using single cell techniques to understand resistance mechanisms to novel immunotherapy agents showing activity against myeloma.
Successful applicants would be part of an established, well funded, committed, and productive interdisciplinary research team of investigators. Ideal candidates would be molecular, cell, and immune biologists with PhD degrees in a closely related field. They should have experience in single cell RNA and TCR sequencing, immunophenotyping and immune assays, and in vivo tumor modeling. He/she should have excellent written and spoken (English) communication skills and promote scientific collaboration within the research group.
For those interested, please send a CV, contact information for three references (preferably three letters of recommendation), and a 2 page research statement describing past achievements, skills and research interests to Dr. Robert Orlowski (email@example.com) and Trish Waitschies (PMWaitschies@mdanderson.org).
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html