Bioinformatics Programmer I

Baylor College of Medicine

Houston, TX

Job posting number: #7108167 (Ref:12633-en_US)

Posted: August 16, 2022

Application Deadline: Open Until Filled

Job Description


We are hiring a bioinformatics programmer with a special focus on image data analysis in the Lester and Sue Smith Breast Center at Baylor College of Medicine. The Breast Center is a collaborative environment dedicated to breast health and disease research, as well as prevention, diagnosis, and treatment of different forms of breast cancer. We are looking for a candidate with a background in computational biology/bioinformatics and a focus on image analysis. 


The prospective will be working in a new laboratory headed by a computational biology principal investigator recently funded by CPRIT. The laboratory is interested in integrating pathology imaging data and spatial genomics data to better understand the contribution of spatial multi-cellular environments to cancer formation and progression, and to understand the biological and clinical relevance of various morphological image features extracted from cell images.

Job Duties

  • Evaluate existing bioinformatic tools.
  • Develop new bioinformatics pipelines for image data analysis and integration.
  • Summarize research findings using sound statistics and informative plots/figures.
  • Present results in lab meetings and to collaborators. 
  • Collaborate with investigators in the breast center.
  • Download data from repositories for public data integration, interrogation, and hypothesis generation.

Minimum Qualifications

  • Bachelor's degree in Computer Science, Biological Science, or a related field.
  • No experience required.

Preferred Qualifications

  • Candidate should have good communication and written skills and good interpersonal skill. In addition, the candidate should be comfortable working with large-scale datasets (single cell and imaging data), and working in the high-performance computing (HPC) environment.  
  • Must be a team player and work well within a group.
  • ImageJ, FIJI for image viewing and basic manipulation.
  • Cell segmentation tools that work on imaging mass cytometry (IMC), H&E staining, and RNA FISH data.
  • Previous experience analyzing multiplexed single-molecule RNA-FISH data is a plus.
  • Image alignment and registration.
  • Python libraries and Matlab toolkit for image analysis. 
  • TIFF, OME-TIFF format for storing images, and metadata.
  • Any prior experience working with cell images is a plus.



Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.


Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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